posted 40 minutes ago - 26,737 notes - reblog

archiemcphee:

Arbore, a flooring contractor in Madrid, Spain, created these awesome interlocking hardwood pieces in the form of M.C. Escher’s famous geometric Reptiles.

[via Technabob]

posted 49 minutes ago - 1,305 notes - reblog

motivationintohabit:

christianborles:

nuitcorbeau:

Ellen’s response to the ‘Abercrombi& Fitch’ statement.

love her

FITCH PLEASE

And I thought my love for her couldn’t get any bigger.

posted 54 minutes ago - 82,413 notes - reblog
posted 1 hour ago - 26,756 notes - reblog

“For me, ‘Dog Days’ symbolizes apocalyptic euphoria, chaotic freedom and running really, really fast with your eyes closed”
“For me, ‘Dog Days’ symbolizes apocalyptic euphoria, chaotic freedom and running really, really fast with your eyes closed”

posted 2 days ago - 5,235 notes - reblog
cuqid:

but mac miller

cuqid:

but mac miller

posted 3 days ago - 27,121 notes - reblog
scinerds:


Scientists Report First Success in Cloning Human Stem Cells

It’s been 17 years since Dolly the sheep was cloned from a mammary cell. And now scientists applied the same technique to make the first embryonic stem cell lines from human skin cells.
Ever since Ian Wilmut, an unassuming embryologist working at the Roslin Institute just outside of Edinburgh stunned the world by cloning the first mammal, Dolly, scientists have been asking – could humans be cloned in the same way? Putting aside the ethical challenges the question raised, the query turned out to involve more wishful thinking than scientific success. Despite the fact that dozens of other species have been cloned using the technique, called nuclear transfer, human cells have remained stubbornly resistant to the process.
Until now. Shoukhrat Mitalipov, a professor at Oregon Health & Science University and his colleagues report in the journal Cell that they have successfully reprogrammed human skin cells back to their embryonic state. The purpose of the study, however, was not to generate human clones but to produce lines of embryonic stem cells. These can develop into muscle, nerve, or other cells that make up the body’s tissues. The process, he says, took only a few months, a surprisingly short period to reach such an important milestone.
Nuclear transfer involves inserting a fully developed cell – in Mitalipov’s study, the cells came from the skin of fetuses – into the nucleus of an egg, and then manipulating the egg to start dividing, a process that normally only occurs after it has been fertilized by a sperm. After several days, the ball of cells that results contains a blanket of embryonic stem cells endowed with the genetic material of the donor skin cell, which have the ability to generate every cell type from that donor. In Dolly’s case, those cells were allowed to continue developing into an embryo that was then transferred to a ewe to produce a cloned sheep. But Mitalipov says his process with the human cells isn’t designed to generate a human clone, but rather just to create the embryonic stem cells. These could then be manipulated to create heart, nerve or other cells that can repair or treat disease.
“I think this is a really important advance,” says Dieter Egli, an investigator at the New York Stem Cell Foundation. “I have a very high confidence that versions of this technique will work very well; it’s something that the field has been waiting for.” Egli is among the handful of scientists who have been working to perfect the technique with human cells and in 2011, succeeded in producing human stem cells, but with double the number of chromosomes. In 2004, Woo Suk Hwang, a veterinary scientist at Seoul National University, claimed to have succeeded in achieving the feat, but later admitted to faking the data. Instead of generating embryonic stem cell lines via nuclear transfer, Hwang’s group produced the stem cells from days-old embryos, a technique that had already been established by James Thomson at University of Wisconsin in 1998.

Full Article

scinerds:

Scientists Report First Success in Cloning Human Stem Cells

It’s been 17 years since Dolly the sheep was cloned from a mammary cell. And now scientists applied the same technique to make the first embryonic stem cell lines from human skin cells.

Ever since Ian Wilmut, an unassuming embryologist working at the Roslin Institute just outside of Edinburgh stunned the world by cloning the first mammal, Dolly, scientists have been asking – could humans be cloned in the same way? Putting aside the ethical challenges the question raised, the query turned out to involve more wishful thinking than scientific success. Despite the fact that dozens of other species have been cloned using the technique, called nuclear transfer, human cells have remained stubbornly resistant to the process.

Until now. Shoukhrat Mitalipov, a professor at Oregon Health & Science University and his colleagues report in the journal Cell that they have successfully reprogrammed human skin cells back to their embryonic state. The purpose of the study, however, was not to generate human clones but to produce lines of embryonic stem cells. These can develop into muscle, nerve, or other cells that make up the body’s tissues. The process, he says, took only a few months, a surprisingly short period to reach such an important milestone.

Nuclear transfer involves inserting a fully developed cell – in Mitalipov’s study, the cells came from the skin of fetuses – into the nucleus of an egg, and then manipulating the egg to start dividing, a process that normally only occurs after it has been fertilized by a sperm. After several days, the ball of cells that results contains a blanket of embryonic stem cells endowed with the genetic material of the donor skin cell, which have the ability to generate every cell type from that donor. In Dolly’s case, those cells were allowed to continue developing into an embryo that was then transferred to a ewe to produce a cloned sheep. But Mitalipov says his process with the human cells isn’t designed to generate a human clone, but rather just to create the embryonic stem cells. These could then be manipulated to create heart, nerve or other cells that can repair or treat disease.

“I think this is a really important advance,” says Dieter Egli, an investigator at the New York Stem Cell Foundation. “I have a very high confidence that versions of this technique will work very well; it’s something that the field has been waiting for.” Egli is among the handful of scientists who have been working to perfect the technique with human cells and in 2011, succeeded in producing human stem cells, but with double the number of chromosomes. In 2004, Woo Suk Hwang, a veterinary scientist at Seoul National University, claimed to have succeeded in achieving the feat, but later admitted to faking the data. Instead of generating embryonic stem cell lines via nuclear transfer, Hwang’s group produced the stem cells from days-old embryos, a technique that had already been established by James Thomson at University of Wisconsin in 1998.

Full Article

posted 3 days ago - 1,098 notes - reblog
posted 3 days ago - 3,676 notes - reblog
posted 3 days ago - 23,055 notes - reblog

time-sponges:

dietchola:

the guy who played all of the oompa loompas in charlie and the chocolate factory is named deep roy

image

deep roy

Deep roy the chocolate boy

posted 4 days ago - 47,176 notes - reblog

overaaalls:

when i look at myself in the mirror i feel like one of those really detailed spongebob paintings

image

posted 5 days ago - 93,213 notes - reblog
posted 5 days ago - 19,297 notes - reblog

brooklynandmusic:

rainbowreverie21:

my-placenta-is-on-fire:

scarecrowartist:

bekkaa:

sweeter-than-tea:

Did you know that by spelling the english word SOCKS outloud, you are also saying the spanish phrase Eso si que es, which means “it is what is is”. 

My spanish teacher told us this last year and I will never forget it

can we  say socks instead of yolo?

yes.

Mama, just killed a man #SOCKS

this here is some real shit

posted 5 days ago - 174,543 notes - reblog
the-bitch-goddess-success:

youngblackandvegan:

satanic2chainz:

extraordinarybrother:

princethepurpleking:

Sisters are evil

I laughed at this shit for like 5min

oh my god

#shortpeoplesrevenge

Actual Troll Master

the-bitch-goddess-success:

youngblackandvegan:

satanic2chainz:

extraordinarybrother:

princethepurpleking:

Sisters are evil

I laughed at this shit for like 5min

oh my god

#shortpeoplesrevenge

Actual Troll Master

posted 5 days ago - 146,074 notes - reblog
spiritualinspiration:

Many people expect the voice of God to boom like a loudspeaker, but scripture tells us that He speaks in a still, small voice. To us, it seems like an impression inside.

We think, “I know I should go visit my parents. I know I shouldn’t eat so many sweets. I know I should stay home and do my schoolwork.” The “I knows” are God talking to you. Don’t ignore it. Learn to be quick to obey.

A lot of times we know what we should do, but we make excuses and reason it out. “I’ll do it later. I’m busy now.” But, we have to understand God doesn’t ask us to do it for His sake. He asks us to do it for our own sake. I’ve learned that before God will release big blessings, He will give you small tests. Too often we dismiss it and think, “Oh, that’s no big deal.” But if you don’t pass these small tests, it will keep you from the big things God has in store.

Today, don’t put off the little things that you know you should be doing any longer. Take a step of faith and obey Him. As you’re faithful in the little things and pass the small tests, He’ll lead you into the greater things He has in store for you.

spiritualinspiration:

Many people expect the voice of God to boom like a loudspeaker, but scripture tells us that He speaks in a still, small voice. To us, it seems like an impression inside.

We think, “I know I should go visit my parents. I know I shouldn’t eat so many sweets. I know I should stay home and do my schoolwork.” The “I knows” are God talking to you. Don’t ignore it. Learn to be quick to obey.

A lot of times we know what we should do, but we make excuses and reason it out. “I’ll do it later. I’m busy now.” But, we have to understand God doesn’t ask us to do it for His sake. He asks us to do it for our own sake. I’ve learned that before God will release big blessings, He will give you small tests. Too often we dismiss it and think, “Oh, that’s no big deal.” But if you don’t pass these small tests, it will keep you from the big things God has in store.

Today, don’t put off the little things that you know you should be doing any longer. Take a step of faith and obey Him. As you’re faithful in the little things and pass the small tests, He’ll lead you into the greater things He has in store for you.

posted 5 days ago - 880 notes - reblog
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